Pharmacology Practice Questions: Test Your Knowledge | LearnByTeaching.ai

A drug has a half-life of 6 hours. Approximately how long will it take to reach steady-state concentration with repeated dosing?

Which parameter best describes the amount of drug reaching systemic circulation unchanged after oral administration?

A competitive antagonist at a receptor will cause what change to the dose-response curve of the agonist?

A drug with a large volume of distribution (Vd) is most likely to have which property?

Zero-order elimination kinetics means that:

Which cytochrome P450 enzyme is responsible for metabolizing the largest number of clinically used drugs?

An elderly patient on warfarin starts taking a CYP2C9 inhibitor. What is the expected clinical consequence?

The therapeutic index is calculated as:

Which route of administration completely bypasses first-pass metabolism?

A partial agonist at a receptor will do which of the following when administered with a full agonist?

Atropine blocks which type of receptor?

A patient on a non-selective beta-blocker would be expected to experience which of the following?

Which drug acts by inhibiting the Na+/K+ ATPase pump in cardiac myocytes?

ACE inhibitors can cause hyperkalemia because they:

Which class of antihypertensive is most associated with the side effect of a dry cough?

Nitroglycerin relieves angina primarily by:

Phenylephrine, a selective alpha-1 agonist, is used as a nasal decongestant because it:

Which antiarrhythmic drug class works primarily by blocking sodium channels and slowing phase 0 depolarization?

A patient with heart failure is started on carvedilol. This drug acts by blocking:

Epinephrine reversal refers to the phenomenon where epinephrine causes hypotension instead of hypertension when administered after:

Penicillins exert their bactericidal effect by:

Which antibiotic class is most associated with tendon rupture as an adverse effect?

Aminoglycosides (e.g., gentamicin) require therapeutic drug monitoring primarily because of their:

Methotrexate exerts its anticancer effect primarily by inhibiting:

Which antifungal works by binding to ergosterol in the fungal cell membrane, creating pores?

Vancomycin's primary mechanism of action is:

Which mechanism of bacterial resistance involves enzymatic destruction of the antibiotic?

Cisplatin causes cancer cell death primarily through:

Which antibiotic should be avoided in children under 8 years old due to tooth discoloration?

Trastuzumab (Herceptin) is a monoclonal antibody used in breast cancer that targets:

SSRIs (selective serotonin reuptake inhibitors) treat depression by:

Benzodiazepines enhance the effect of GABA by:

Levodopa is combined with carbidopa in the treatment of Parkinson's disease because carbidopa:

Naloxone is used to reverse opioid overdose because it is a:

Which thyroid drug works by inhibiting the enzyme thyroid peroxidase?

Metformin lowers blood glucose in type 2 diabetes primarily by:

Lithium, used as a mood stabilizer in bipolar disorder, requires monitoring of which organ's function?

The antiepileptic drug that works by blocking T-type calcium channels and is first-line for absence seizures is:

Corticosteroids (e.g., prednisone) are associated with all of the following adverse effects EXCEPT:

Sumatriptan is used to treat acute migraines by acting as an agonist at which receptor?